Calcium and transmitter release at nerve terminals.
نویسنده
چکیده
Dolphin, A. C. and Scott, R. H. (1987) J. Physiol. (London) 386, 1-17 Holz, G. G., Rane, S. G. and Dunlap, K. (1986) Nature (London) 319,670-672 Scott, R. H. and Dolphin, A. C. (1986) Neurosci. Lett. 69,59-64 Lewis, D. L., Weight, F. F. and Luini, A. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 9035-9039 Grassi, F. and Lux, H. D. (1989) Neurosci. Lett. 105, 113-1 19 Dolphin, A. C., Huston, E. and Scott, R. H. (1990) Biochem. SOC. Symp. 56,45-60 Marchetti, C. and Robello, M. (1989) Hiophys. J. 56, 1267-1272 Dolphin, A. C. and Scott, R. H. (1989) J. Physiol. (London) 413,271-288 Scott, R. H. and Dolphin, A. C. (1990) Br. J. Pharmacol. 99,629-630 Dolphin, A. C. (1992) Pflugers Arch. 421, 138-145 Dolphin, A. C. (1991) J. Physiol. (London) 432, 23-43 Harris-Warwick, R. M., Hammond, C., PaupardinTritsch, D., Homburger, V., Rouot, B., Bockaert, J. and Gerschenfeld, H. M. (1988) Neuron 1,27-32 Lledo, P. M., Homburger, V., Bockaert. J. and Vincent, J.-D. (1992) Neuron 8,455-463 McFadzean, I., Mullaney, I. and Brown, D. A. (1989) 199-207 26.
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عنوان ژورنال:
- Biochemical Society transactions
دوره 21 2 شماره
صفحات -
تاریخ انتشار 1993